The Beauty Brains: Can Peptides Stop Facial Wrinkles?

The Beauty Brains Cosmetic chemists answer your beauty product questions! We are a group of cosmetic scientists who understand what the chemicals used in cosmetics really do, how products are tested, and what all the advertising means.

Can Peptides Stop Facial Wrinkles? Aug 25th 2012, 06:01 Jeanne asks…Which peptides in face creams are most effective in communicating with facial muscles to cause shortening of them and therefore firming the face? The Right Brain responds: According to at least one study, acetyhlexapeptide-8 is capable of reducing wrinkles associated with facial muscles. How peptides work This peptide allegedly works similarly to botulintoxin, aka Botox (™), by inhibiting what is known as the SNARE complex which results in reduced muscle contractions. But unlike Botox (™), this peptide does not irreversibly destroy a key protein – its effect is temporary. Acetyhlexapeptide-8 is also supposedly able to relax the collagen and elastin matrix by altering calcium ion uptake. The Beauty Brains bottom line We’re skeptical because we don’t know the type and concentration of acetyhlexapeptide-8 used in any given product. Still, there seems to be at least some scientific basis for using this peptide to fight facial wrinkles. Reference: J. Cosmet. Sci.,58, 157-171 (March/April 2007) Image credit: http://schaver.com/wp-content/images/face.png

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